I am a huge fan of Yellow Mug’s Filechute ($18) to share larger files through MobileMe (or any other server). But this online file hosting service allows you to upload your files for free (up to 5 GB). Just send the the recipient a link where your stuff can be downloaded. Fast and easy to use.
Alternatively you could use YouSendIt, or Apple’s own iDisk solution, but both gave me headaches in the past.
